Cluster Randomized Trial Designs in Cancer Care Delivery Research, NCI

Purpose:

The National Cancer Institute (NCI) invites attendance for a virtual short course that will provide training in the design, conduct, and analysis of cluster randomized trials (CRTs), including parallel CRTs, stepped-wedge CRTs, and cluster randomized cross-over trials (CRXO). The course is jointly sponsored by NCI’s Healthcare Delivery Research Program and Implementation Science Team. CRTs are increasingly used to evaluate interventions to improve care delivery and to study strategies for implementing evidence-based interventions into routine clinical practice. They require specific methods of design and statistical analysis. The course will address the rationale for using these designs, specific design considerations, the randomization process, sample size calculations, analytic methods, ethical considerations, practical issues in trial management, and trial reporting and interpretation. Principles will be illustrated using case studies of the different variations of CRTs across the cancer control continuum (prevention, diagnosis, treatment, survivorship, and at end-of-life).

Intended Audience:

This course will address the training needs of doctorally prepared cancer care delivery researchers and implementation scientists, as well as post-doctoral fellows and other trainees, and other scientific team members such as project coordinators. Some of the sessions are specifically targeted at statisticians, methodologists, and researchers with an interest in more complex statistical topics.

Participation in the course is free of charge, but registration is required.

Questions about the workshop may be submitted at https://healthcaredelivery.cancer.gov/about/contact.html

For more information and to register, visit https://events.cancer.gov/nci/clustertrials.