A framework for implementing patient-reported outcomes in clinical care: the PROTEUS-practice guide

Jun 01, 2024 | Crossnohere

Patient-reported outcomes (PROs) are a powerful tool for clinical practice that directly measure patient experiences, enabling providers to tailor care to patients’ needs and priorities. PROs are patients’ own reports of how they feel, function, and live their lives1, collected using standardized, validated questionnaires. Compelling evidence demonstrates the value of using PROs in clinical practice, whereby a healthcare provider and a patient together use the patient’s PROs to inform care. Implementing PROs as part of routine care can facilitate patient–provider communication, help to identify and address healthcare problems, increase efficiency, and improve patient outcomes, such as symptom burden, functioning, quality of life, and even survival. Measurement of PROs is an integral part of innovative payment models, including the Centers for Medicare and Medicaid Services ‘Enhancing Oncology Model’ and ‘Comprehensive Primary Care Plus’ (CPC+) model, and contributes to quality metrics such as Newsweek’s 2023 ranking of the world’s best specialized hospitals. https://theproteusconsortium.org/proteus-practice/

PubMed Abstract


Crossnohere NL, Anderson N, Baumhauer J, Calvert M, Esparza R, Gulbransen S, Haverman L, Li Y, Petersen C, Retzer A, Sidey-Gibbons C, Stover AM, Thorner E, Ursin G, Velikova G, Sparkman Walker E, Brundage M, Snyder C. A Framework for Implementing Patient-Reported Outcomes in Clinical Care: The PROTEUS-Practice Guide. Nature Med; 2024;30:1519–1520. https://doi.org/10.1038/s41591-024-02909-8