Perspectives from NHLBI Global Health Think Tank Meeting for Late Stage (T4) Translation Research.

Dec 04, 2017 | Engelgau MM, Peprah E, Sampson UKA, Mishoe H, Benjamin IJ, Douglas PS, Hochman JS, Ridker PM, Brandes N, Checkley W, El-Saharty S, Ezzati M, Hennis A, Jiang L, Krumholz HM, Lamourelle G, Makani J, Narayan KMV, Ohene-Frempong K, Straus SE, Stuckler D, Chambers DA, et al.

Almost three-quarters (74%) of all the noncommunicable disease burden is found within low- and middle-income countries. In September 2014, the National Heart, Lung, and Blood Institute held a Global Health Think Tank meeting to obtain expert advice and recommendations for addressing compelling scientific questions for late stage (T4) research-research that studies implementation strategies for proven effective interventions-to inform and guide the National Heart, Lung, and
Blood Institute’s global health research and training efforts. Major themes emerged in two broad categories: 1) developing research capacity; and 2) efficiently defining compelling scientific questions within the local context. Compelling scientific questions included how to deliver inexpensive, scalable,
and sustainable interventions using alternative health delivery models that leverage existing human capital, technologies and therapeutics, and entrepreneurial strategies. These broad themes provide perspectives that inform an overarching strategy needed to reduce the heart, lung, blood, and sleep
disorders disease burden and global health disparities.

PubMed Abstract

Glob Heart. 2017 Dec;12(4):341-348. doi: 10.1016/j.gheart.2016.03.640. Epub 2016 Jul 21.